| Goaltenders: | ||||||
| Goaltender | Record | Sv % | GAA | Shutouts | ||
| Al Montoya vs. BUF | 1-0 | .857 | 3.15 | 0 | ||
| Jhonas Enroth vs. NYI | 0-0 | .000 | 0.00 | 0 | ||
| Sabres Leading Scorers: | ||||||
| Player | GP | G | A | P | ||
| Thomas Vanek | 23 | 12 | 14 | 26 | ||
| Jason Pominville | 23 | 9 | 16 | 25 | ||
| Luke Adam | 23 | 8 | 8 | 16 | ||
| Derek Roy | 23 | 6 | 10 | 16 | ||
| Christian Ehrhoff | 23 | 2 | 11 | 13 | ||
| Islanders Leading Scorers: | ||||||
| Player | GP | G | A | P | ||
| John Tavares | 21 | 8 | 8 | 16 | ||
| PA Parenteau | 21 | 3 | 12 | 15 | ||
| Matt Moulson | 21 | 7 | 5 | 12 | ||
| Michael Grabner | 21 | 7 | 4 | 11 | ||
| Mark Streit | 21 | 2 | 9 | 11 | ||
| Special Teams: | ||||||
| Team | Power Play | NHL Rank | Penalty Kill | NHL Rank | ||
| Buffalo Sabres | 19.3% | 8th | 88.4% | 5th | ||
| New York Islanders | 14.5% | 20th | 80% | 24th | ||
| 2010-2011 Season Series | ||||||
| Date | Matchup | Result | ||||
| 1/15/11 | Islanders 5, Buffalo 3 | Loss (OT) | ||||
| 1/21/11 | Islanders 5, Buffalo 2 | Loss | ||||
| 1/23/11 | Buffalo 5, Islanders 3 | Win | ||||
| 2/13/11 | Islanders 7, Buffalo 6 | Loss (OT) | ||||