The Sabres were unable to finish off the road trip with a victory, losing 4-3 to Toronto on Saturday night. Buffalo, who were 17-1-2 leading after two periods, allowed the Maple Leafs to score two goals in the third period to win the game.
Buffalo outshot the Leafs 42-29 on the night, but were unable to tie the game in the latter half of the third period. Despite the loss, the Sabres finished the seven game road trip with a 4-2-1 record.
The Sabres got off to a quick start against Toronto. Mike Weber took a wrist shot from the point that found its way past James Reimer to put Buffalo up 1-0.
Former Sabre Clarke MacArthur scored his 20th of the season after he fired a shot that went off the post and into the net to tie the game at one.
The Toronto power play has not scored against Buffalo in its last 41 attempts. Ryan Miller made sure of it when he robbed Joffrey Lupul of a goal in the opening period. Lupul got a hold of a rebound and had a point-blank shot, but Miller made a pad save.
Miller stopped Tyler Bozak on a breakaway to keep the game tied. 
The Leafs had the Sabres pinned in their own end and Bozak was left all alone in front of the net. This time, Bozak beat Miller, and the Leafs took a 2-1 lead.
The resilient Sabres came right back to tie the game at two. Jochen Hecht banked home a rebound.
Jordan Leopold capitalized on the first power play opportunity for the Sabres. Leopold’s 12th goal of the season not only put Buffalo up 3-2, but it also gave him a new career-high in goals.
The Sabres registered 20 shots on goal in the 2nd period.
Mikael Grabovski knotted the game at three early in the third period as Miller was unable to get across the crease and stop the one-timer.
Toronto continued to put pressure on the Sabres, and it paid off. Phil Kessel shot the puck toward the net and scored as the puck deflected off of Steve Montador and into the net.
The Sabres special teams killed off both penalties, making it 42 straight against Toronto. Buffalo’s power play only had one opportunity, which they scored on.
The Sabres will head home to host the Senators Sunday at 5 p.m.