| Goaltenders vs. Opponent | ||||
| Goaltender | Record | Sv % | GAA | Shutouts |
| Ryan Miller vs. PIT | 4-9-3 | .879 | 3.45 | 0 |
| M.A. Fleury vs. BUF | 11-4-2 | .909 | 2.62 | 1 |
| Sabres Leading Scorers: | ||||
| Player | GP | G | A | PTS |
| Jason Pominville | 58 | 22 | 32 | 54 |
| Thomas Vanek | 55 | 21 | 23 | 44 |
| Derek Roy | 56 | 11 | 18 | 29 |
| Drew Stafford | 58 | 9 | 18 | 27 |
| Nathan Gerbe | 47 | 5 | 16 | 21 |
| Penguins Leading Scorers: | ||||
| Player | GP | G | A | PTS |
| Evgeni Malkin | 51 | 32 | 38 | 70 |
| James Neal | 58 | 30 | 26 | 56 |
| Chris Kunitz | 58 | 16 | 25 | 41 |
| Pascal Dupuis | 58 | 13 | 20 | 33 |
| Kris Letang | 35 | 8 | 21 | 29 |
| Special Teams: | ||||
| Team | PP | Rank | PK | Rank |
| Buffalo Sabres | 16.2% | 20th | 80.5% | 24th |
| Pittsburgh Penguins | 19.3% | 7th | 88.1% | 3rd |